Production of 1,25-dihydroxyvitamin D3 by human T cell lymphotrophic virus-I-transformed lymphocytes.
نویسندگان
چکیده
منابع مشابه
Transformed T lymphocytes infected by a novel isolate of human T cell leukemia virus type II.
Human T cell leukemia virus type II (HTLV-II) has been isolated from a patient (Mo) with features of leukemic reticuloendotheliosis (LRE) and from a patient with acquired immunodeficiency syndrome (AIDS). We have obtained another isolate of HTLV-II from a patient (CM) with severe hemophilia A, pancytopenia, and a 14-year history of staphylococcal and candidal infections but no evidence of T cel...
متن کاملTransformed T Lymphocytes Infected by a Novel Isolate of Human T Cell Leukemia Virus Type
Human T cell leukemia virus type II (HTLV-lI) has been isolated from a patient (Mo) with features of leukemic reticuloendotheliosis (IRE) and from a patient with acquired immunodeficiency syndrome (AIDS). We have obtained another isolate of HTLV-ll from a patient (CM) with severe hemophilia A, pancytopenia. and a 14-year history of staphylococcal and candidal infections but no evidence of T cel...
متن کاملElevated cyclic AMP levels in T lymphocytes transformed by human T-cell lymphotropic virus type 1.
Human T-cell lymphotropic virus type 1 (HTLV-1), the cause of adult T-cell leukemia/lymphoma (ATLL), transforms CD4(+) T cells to permanent growth through its transactivator Tax. HTLV-1-transformed cells share phenotypic properties with memory and regulatory T cells (T-reg). Murine T-reg-mediated suppression employs elevated cyclic AMP (cAMP) levels as a key regulator. This led us to determine ...
متن کامل1,25-Dihydroxyvitamin D3 production by human keratinocytes. Kinetics and regulation.
Human foreskin keratinocytes in vitro metabolize 25-hydroxyvitamin D3 to a number of metabolites, including 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). This metabolite remains mostly within the cell and does not accumulate in the medium under the conditions of these experiments. With time, 1,25(OH)2D3 is catabolized, and more polar metabolites appear in both the cells and the medium. The production...
متن کاملAge distribution among patients at high risk for human T-cell lymphotrophic virus type I infection.
1. Boivin G, Edelman CK, Pedneault L, Talarico CL, Biron KK, Balfour HH Jr. Phenotypic and genotypic characterization of acyclovir-resistant varicella-zoster viruses isolated from persons with AIDS. J Infect Dis 1994; 170:68-75. 2. Erlich KS, Mills J, Chatis P, et al. Acyclovir-resistant herpes simplex virus infections in patients with the acquired immunodeficiency syndrome. N Engl J Med 1989;3...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1986
ISSN: 0021-9738
DOI: 10.1172/jci112614